Project Title:
A Next-Generation Platform for Novel Drug Discovery Using Deep Learning of ADMET Properties.
Acronym:
DeepADMET
Call:
Innovate UK Health & Life Sciences
Start Date:
01/09/2018
Duration:
24 months
Grant Amount:
£819,988
Our Role:
Bid Writing
DeepADMET aims to create a "next generation" platform providing novel methods for compound selection and design for drug discovery purposes, building on Optibrium's current software, StarDropTM. Through expanding the range of ADMET properties that can be modelled and improving their reliability by applying modern 'deep learning' methods, Optibrium can improve the accuracy and applicability of these models. Proof-of-concept work indicates their methods provide a unique advantage over 'off-the-shelf' deep learning methods when applied to sparse, uncertain data of the type found in drug discovery.
DeepADMET aims to create a "next generation" platform providing novel methods for compound selection and design for drug discovery purposes, building on Optibrium's current software, StarDropTM. Through expanding the range of ADMET properties that can be modelled and improving their reliability by applying modern 'deep learning' methods, Optibrium can improve the accuracy and applicability of these models. Proof-of-concept work indicates their methods provide a unique advantage over 'off-the-shelf' deep learning methods when applied to sparse, uncertain data of the type found in drug discovery.