Project Title:

A Next-Generation Platform for Novel Drug Discovery Using Deep Learning of ADMET Properties.


Acronym:

DeepADMET


Call:

Innovate UK Health & Life Sciences


Start Date:

01/09/2018


Duration:

24 months


Grant Amount:

£819,988


Our Role:

Bid Writing


DeepADMET aims to create a "next generation" platform providing novel methods for compound selection and design for drug discovery purposes, building on Optibrium's current software, StarDropTM. Through expanding the range of ADMET properties that can be modelled and improving their reliability by applying modern 'deep learning' methods, Optibrium can improve the accuracy and applicability of these models. Proof-of-concept work indicates their methods provide a unique advantage over 'off-the-shelf' deep learning methods when applied to sparse, uncertain data of the type found in drug discovery.

DeepADMET aims to create a "next generation" platform providing novel methods for compound selection and design for drug discovery purposes, building on Optibrium's current software, StarDropTM. Through expanding the range of ADMET properties that can be modelled and improving their reliability by applying modern 'deep learning' methods, Optibrium can improve the accuracy and applicability of these models. Proof-of-concept work indicates their methods provide a unique advantage over 'off-the-shelf' deep learning methods when applied to sparse, uncertain data of the type found in drug discovery.